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Curr Opin Neurobiol 17 : 243250

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Since the mevalonate pathway is closely related to ferroptosis through regulating expression of GPX4, production of squalene and coenzyme Q, and sterols are known to exert intricate feed-back regulations on this pathway to restrict cholesterol overproduction, we hypothesized that cholesterol and its metabolites would modulate cell sensitivity to ferroptosis

doi: 10.3390/ijms23042342 110 LeeH-RYooS-JKimJParkCKKangSW